Spot clean with damp cloth.
As a stay at home mother of 4 children, I can honestly say that the DockATot has been by far the best baby product I have ever bought. I am currently using the Deluxe DockATot for my 8 week old, baby Mikey. We have been using it since we arrived home from the hospital. When I put baby Mikey in his DockATot, I can visibly see him relax and begin to sooth himself to get ready to sleep.